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Quantity: 100 ul                                                                                       Application: WB

Predicted I Observed M.W.: 62 I 56 kDa                                                  Uniprot ID: O75914

Background:

Serine/threonine-protein kinase PAK 3 (PAK3) belongs to the protein kinase superfamily, the STE Ser/Thr protein kinase family, and the STE20 subfamily. PAK3 is a serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. PAK3 plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Additionally, PAK3 acts as downstream effector of the small GTPases CDC42 and RAC1.

Other Names:

Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3, OPHN3

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human PAK3. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: