R0107-vp - BCL6 (vPairTM) Antibodies

Catalog No. R0107-vp
Product Name BCL6 (vPairTM) Antibodies
Price $249

Predicted I Observed M.W.: 79 I 100 kDa                                                   Uniprot ID: P41182

Application: WB

Quantity:        50 ul BCL6 (N1) (R0107-1) Rabbit Polyclonal Antibody &

                        50 ul BCL6 (N2) (R0107-2) Rabbit Polyclonal Antibody 

Product Introduction:

vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.


B-cell CLL/lymphoma 6 (BCL6) is a zinc finger transcription factor that acts as a sequence-specific repressor of transcription.  It has been shown to regulate the transcription of STAT-dependent IL-4 responses of B cells.  It contains an N-terminal POZ domain that interacts with other proteins to function as transcription co-repressors.  The gene encoding BCL6 protein has been found to be translocated and mutated in diffuse large-cell lymphoma (DLCL) and may play a role in the pathogenesis of DLCL.                                                                      

Other Names:

B-cell lymphoma 6 protein, B-cell lymphoma 5 protein, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, zinc finger protein 51, BCL5, LAZ3, ZBTB27, ZNF51, BCL6A

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing 2 distinct N-terminal regions of human BCL6.  Antibodies were purified by affinity purification using immunogen. 

Species Specificity:

Human, Mouse

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Recommended Conditions: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

BCL6 Antibody Western (Abiocode)

Fig 1. Western blot of total cell extracts from
(A, C) mouse brain, (B) human Jurkat; using 2
independent Abs against 2 distinct regions of
human BCL6 at RT for 2 h.