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R3118-2 - PANX1 (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 48 I 48, 56 kDa Uniprot ID: Q96RD7 Background: Pannexin-1 (PANX1) is a multi-pass membrane protein and a structural component of the gap junctions and the hemichannels. PANX1 may play a role as a Ca2+-leak channel to regulate ER Ca2+ homeostasis. Other Names: Pannexin-1, MRS1 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing C-terminal region of human PANX1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from A) mouse brain,B) human HeLa, C) human Jurkat; using anti-PANX1 (C) (R3118-2) at RT for 2 h. This Ab recognizes the 48 kD and 56 kD bands, which may represent non-glycosylated and glycosylated PANX1, respectively. |