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Quantity: 100 ul                                                                                           Application: WB, IP

Predicted I Observed M.W.: 49 kDa                                                             Uniprot ID: Q9UMR3

Background:

TBX20 is a member of the T-box family of transcription factors. TBX20 is a nuclear protein containing 1 T-box DNA-binding domain. Studies in mouse, human and fruitfly have shown that TBX20 is essential for early heart development, adult heart function and yolk sac vasculature remodeling and has been associated with congenital heart diseases. Proper function of TBX20 is essential because it controls genes that regulate cardiomyocyte proliferation, such as Tbx2 and N-myc1. TBX20 is also required for migration of hindbrain motor neurons; while in facial neurons, TBX20 is proposed to be a positive regulator of the non-canonical Wnt signaling pathway. Defects in TBX20 are the cause of atrial septal defect type 4 (ASD4).

Other Names:

T-box transcription factor TBX20, T-box protein 20

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human TBX20. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

IP: 1:100-1:200

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: