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R1509-1 - DRD3 (M) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 44 I 52, 65 kDa Uniprot ID: P35462 Background: DRD3 inhibits adenylyl cyclase through inhibitory G-proteins. DRD3 is expressed in phylogenetically older regions of the brain, suggesting that this receptor plays a role in cognitive and emotional functions. DRD3 is a target for drugs which treat schizophrenia, drug addiction, and Parkinson's disease. Other Names: Dopamine D3 receptor Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human DRD3. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: (B) mouse thymus, (C) human HeLa, (D) human Jurkat; using anti-DRD3 (C) (R1509-2) at RT for 2 h. The 65 kD bands may represent glycosylated DRD3 [Jeanneteau F. et al., PNAS (2006) 103:10753]. |