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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 70 kDa                                                            Uniprot ID: Q9Y2U5

Background:

MAP3K2, mitogen-activated protein kinase kinase kinase 2, is a member of serine/threonine protein kinase family. MAP3K2 preferentially activates other kinases involved in the MAP kinase signaling pathway. MAP3k2 has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. MAP3K2 has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Other Names:

MAPK/ERK kinase kinase 2, MAPKKK2, MEKK2

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MAP3K2. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: