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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 53.5 kDa                                                         Uniprot ID: P17661

Background:

Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. Defects in DES are the cause of myopathy myofibrillar desmin-related (MFM-DES), also known as desmin-related myopathy (DRM); cardiomyopathy dilated type 1I (CMD1I) and neurogenic scapuloperoneal syndrome Kaeser type (Kaeser syndrome).

Other Names:

DES

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human DESMIN. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: