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Quantity: 100 ul                                                                                             Application: WB

Predicted I Observed M.W.: 58 kDa                                                            Uniprot ID: P37231

Background:

PPARG, peroxisome proliferator-activated receptor gamma, is a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. PPARG is a regulator of adipocyte differentiation. Additionally, PPARG has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Defects in PPARG can lead to type 2 insulin-resistant diabetes and hyptertension. PPARG mutations may be associated with colon cancer. Defects in PPARG may be associated with susceptibility to obesity. Defects in PPARG are the cause of familial partial lipodystrophy type 3. Genetic variations in PPARG can be associated with susceptibility to glioma type 1.

Other Names:

Nuclear receptor subfamily 1 group C member 3, NR1C3, PPARG1, PPARG2, PPARgamma

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human PPARG. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: