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Quantity: 100 ul                                                                    Application: WB

Predicted M.W.: 122 kDa                                                      Uniprot ID: P15941

Background:

Mucin 1 (MUC1) is a member of the mucin family.  It is a membrane bound glycosylated phosphoprotein.  It anchors to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type.  MUC1 can act as an adhesion or anti-adhesion protein.  It also serves a protective function by binding to pathogens and functions in a cell signaling capacity.  Overexpression, aberrant intracellular localization, and changes in glycosylation of MUC1 have been associated with carcinomas.                         

Other Names:

RP11-263K19.2, CD227, EMA, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC-1/Z

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MUC1.  Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.                                                                                      

Product Data: