Products

M0008-1a - Foxp3 (N) Antibody, Mouse Monoclonal

Catalog No. M0008-1a
Product Name Foxp3 (N) Antibody, Mouse Monoclonal
Price $219
  
 

Quantity: 100 ul                                                                                             Application: WB

Predicted M.W.: 47 kDa                                                                                Uniprot ID: Q99JB6

Isotype: mouse IgG2b                                                                                  Clone: 9B3


Background:

Forkhead box p3 (Foxp3) is a member of the forkhead/winged-helix family of transcriptional regulators.  It plays a vital role in immune response.  Mutations in Foxp3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrom (IPEX), also known as X-linked autoimmunity-immunoeficiency syndrome.

Other Names:

RP23-54C14.1, JM2, scurfin, sf

Source and Purity:

Mouse monoclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of mouse Foxp3. Antibodies were purified by Caprylic Acid- Ammonium Sulfate precipitation. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 40% Glycerol, 0.02% Thimerosal. Store at -20 °C. Stable for at least 6 months from date of receipt.

Species Specificity:

Mouse

Tested Applications:

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data:

 Foxp3 Antibody Western (Abiocode)

Fig 1.  Western blot of total cell extracts from
(A) murine CD4+CD25- naïve T cells, (B) murine
CD4+CD25+ Treg cells, using Ab (M0008-1a) at
RT for 2 h.