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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 92 kDa                                                            Uniprot ID: Q9UDY8

Background:

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) belongs to the peptidase C14B family and enhances BCL10-induced activation of NF-kappa-B. MALT1 is involved in nuclear export of BCL10. Additionally, MALT1 binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. MALT1 has ubiquitin ligase activity, and MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Other Names:

Mucosa-associated lymphoid tissue lymphoma translocation protein 1, MALT lymphoma-associated translocation, Paracaspase, MLT

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MALT1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: