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Quantity: 100 ul                                                                                       Application: WB

Predicted I Observed M.W.: 63 kDa                                                         Uniprot ID: Q13555

Background:

Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) belongs to the protein kinase superfamily, the CAMK Ser/Thr protein kinase family, and the CaMK subfamily. CAMK2G is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca²⁺/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca²⁺ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, CAMK2G is involved in regulation of sarcoplasmic reticulum (SR) Ca²⁺ transport and in fast-twitch muscle participates in the control of Ca²⁺ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, CAMK2G may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

Other Names:

Calcium/calmodulin-dependent protein kinase type II subunit gamma, CaM kinase II subunit gamma, CaMK-II subunit gamma

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human CAMK2G. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: