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R2406-vp - FSHR (vPairTM) Antibodies
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Predicted I Observed M.W.: 78 I 100 kDa Uniprot ID: P23945 Application: WB Quantity: 50 ul FSHR (N) (R2406-1) Rabbit Polyclonal Antibody & 50 ul FSHR (C1) (R2406-2) Rabbit Polyclonal Antibody Product Introduction: vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Background: Follicle-stimulating hormone receptor (FSHR) belongs to family 1 of G-protein coupled receptors. It is a multi-pass cell membrane protein and is the receptor for follicle stimulating hormone and functions in gonad development. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants of FSHR. Other Names: Follicle-stimulating hormone receptor, FSH-R, Follitropin receptor, FSHRO, LGR1, ODG1 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal [FSHR (N) (R2406-1)] or the C-terminal [FSHR (C1) (R2406-2)] region of human FSHR. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: (A, B) human HeLa; using 2 independent Abs against 2 distinct regions of human FSHR at RT for 2 h. |