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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 87 I 120, 75 kDa                                             Uniprot ID: P16473

Background:

Thyroid-stimulating hormone receptor (TSHR) is a membrane protein and a major controller of thyroid cell metabolism. TSHR is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in the TSHR gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene [provided by RefSeq].

Other Names:

Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R, LGR3

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of human TSHR. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: