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R2695-vp - CBFA2T3 (vPairTM) Antibodies
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Predicted I Observed M.W.: 71 I 80 kDa Uniprot ID: O75081 Application: WB Quantity: 50 ul CBFA2T3 (N) (R2695-1) Rabbit Polyclonal Antibody & 50 ul CBFA2T3 (C) (R2695-2) Rabbit Polyclonal Antibody Product Introduction: vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Background: CBFA2T3 functions as a transcriptional repressor. CBFA2T3 regulates the proliferation and the differentiation of erythroid progenitors by repressing the expression of TAL1 target genes. CBFA2T3 plays a role in granulocyte differentiation. The isoform 2 of CBFA2T3 functions as an A-kinase-anchoring protein. Other Names: Protein CBFA2T3, MTG8-related protein 2, Myeloid translocation gene on chromosome 16 protein, MTG16, Zinc finger MYND domain-containing protein 4, MTGR2, ZMYND4 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal [CBFA2T3 (N) (R2695-1)] or the C-terminal [CBFA2T3 (C) (R2695-2)] region of human CBFA2T3. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from A, D) humanHeLa, B, E) human Jurkat, C) mouse thymus; using 2 independent Abs against 2 distinct regions of human CBFA2T3 at RT for 2 h. |