Abiocode Logo
Products
Contact Us
- Telephone:
1-818-707-0309 - E-Mail:
Abiocode@Abiocode.com
R2724-vp - CDC73 (vPairTM) Antibodies
|
Quantity: 100 ul Application: WB Predicted I Observed M.W.: 60 kDa Uniprot ID: Q6P1J9 Application: WB Quantity: 50 ul CDC73 (N) (R2724-1) Rabbit Polyclonal Antibody & 50 ul CDC73 (C) (R2724-2) Rabbit Polyclonal Antibody Product Introduction: vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Background: CDC73 is involved in transcriptional and post-transcriptional control pathways. CDC73 is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. CDC73 appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in CDC73 have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. Other Names: Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein, C1orf28, HRPT2 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal [CDC73 (N) (R2724-1)] or the C-terminal [CDC73 (C) (R2724-2)] region of human CDC73. Antibodies were purified by affinity purification using immunogen. Species Specificity: Human Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts fromA, C) human HeLa, B, D) human Jurkat; using 2 independent Abs against 2 distinct regions of human CDC73 at RT for 2 h. |