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Quantity: 100 ul                                                                                           Application: WB

Predicted I Observed M.W.: 60 kDa                                                            Uniprot ID: Q9UIF7

Background:

MutY homolog (MUTYH) is a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. MUTYH is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer [provided by RefSeq].

Other Names:

A/G-specific adenine DNA glycosylase, MutY homolog, hMYH, MYH

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human MUTYH. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: