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R1121-1 - TLR5 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 98 I 110 kDa Uniprot ID: O60602 Background: Toll-like receptor 5 (TLR5) is a single-pass type I membrane protein belonging to the Toll-like receptor family. TLR5 participates in the innate immune response to microbial agents. TLR5 mediates detection of bacterial flagellins as well as acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Other Names: Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human TLR5. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: (A) mouse thymus, (B) human Jurkat; using anti-TLR5 (N) (R1121-1) at RT for 2 h. |