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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 24 kDa                                                            Uniprot ID: Q96G30

Background:

Melanocortin-2 receptor accessory protein 2 (MRAP2) is a single-pass type I membrane protein and a  modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. MRAP2 plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP By similarity. MRAP2 may also act as a negative regulator of MC2R by competing with MRAP for binding to MC2R; thus impairing the binding of corticotropin (ACTH) to MC2R.

Other Names:

Melanocortin-2 receptor accessory protein 2, MC2R accessory protein 2, C6orf117

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing C-terminal region of human MRAP2. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: