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Quantity: 100 ul                                                                                          Application: WB

Predicted | Observed MW: 25 | 28 kDa                                                       Uniprot ID: Q05195

Background:

Max dimerization protein 1 (MXD1) is a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. MXD1 antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in the MXD1 gene may play a role in acute leukemia, and the MXD1 protein is a potential tumor suppressor [provided by RefSeq].

Other Names:

Max dimerization protein 1, Max dimerizer 1, Protein MAD

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MXD1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: