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R3131-vp - NPR1 (vPairTM) Antibodies
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Predicted | Observed MW: 119 kDa Uniprot ID: P16066 Application: WB Quantity: 50 ul NPR1 (N) (R3131-1) Rabbit Polyclonal Antibody & 50 ul NPR1 (M) (R3131-2) Rabbit Polyclonal Antibody Product Introduction: vPairTM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPairTM antibodies in the same assay can validate signal specificity since vPairTM antibodies recognize two independent epitopes of the same protein. Different sets of vPairTM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Background: Atrial natriuretic peptide receptor 1 (NPR1) is a single pass type I membrane protein. NPR1 is a receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP, which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. NPR1 has guanylate cyclase activity upon binding of the ligand. Other Names: Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal [NPR1 (N) (R3131-1)] or the middle [NPR1 (M) (R3131-2)] region of human NPR1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts fromA, C) human HeLa, B, D) human Jurkat; using 2 independent Abs against 2 distinct regions of human NPR1 at RT for 2 h. |