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R1518-2 - TP53BP1 (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 214 I 230 kDa Uniprot ID: Q12888 Background: Tumor suppressor p53-binding protein 1 (TP53BP1) plays a key role in the response to DNA damage. TP53BP1 may have a role in checkpoint signaling during mitosis. Also, TP53BP1 enhances TP53-mediated transcriptional activation. Other Names: Tumor suppressor p53-binding protein 1, 53BP1, p53-binding protein 1, p53BP1 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human TP53BP1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts fromA) mouse brain, B) mouse thymus, C) human HeLa, D) human Jurkat; using anti-TP53BP1 (C) (R1518-2) at RT for 2 h. |