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Quantity: 100 ul                                                                                         Application: WB

Predicted I Observed M.W.: 181 I 230 kDa                                                 Uniprot ID: Q9Y6N7

Background:

Roundabout homolog 1 (ROBO1) belongs to the ROBO family and is a single pass type I membrane protein. ROBO1 is a receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. ROBO1 may be required for lung development.

Other Names:

Roundabout homolog 1, Deleted in U twenty twenty, H-Robo-1, DUTT1

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human ROBO1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: