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R1749-1 - RBFOX2 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 41 I 56 kDa Uniprot ID: O43251 Background: RNA binding protein fox-1 homolog 2 (RBFOX2) is an RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements and seems to act as a coregulatory factor of ER-alpha. RBFOX2 prevents binding of U2AF2 to the 3'-splice site. RBFOX2 regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. Other Names: RNA binding protein fox-1 homolog 2, Fox-1 homolog B, Hexaribonucleotide-binding protein 2, RNA-binding motif protein 9, RNA-binding protein 9, Repressor of tamoxifen transcriptional activity, FOX2, HRNBP2, RBM9, RTA Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human RBFOX2. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extractsfrom A) human HeLa; B) human Jurkat; using anti-RBFOX2 (N) (R1749-1) at RT for 2 h. |