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R3174-1 - FANCM (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 156 kDa Uniprot ID: F4HYE4 Background: FANCM is a highly conserved helicase that functions as a major factor limiting meiotic crossover formation. It is not directly involved in the repair of DNA lesions but suppresses spontaneous somatic homologous recombination via a RecQ helicase (At-RECQ4A)-independent pathway. Other Names: Helicase FANCM-like protein, AT-FANCM, FANCM, FANCONI ANEMIA COMPLEMENTATION GROUP M Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of arabidopsis thaliana FANCM (At1g35530). Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Arabidopsis thaliana Tested Applications: WB: 1:500-1:2,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western of protein extracts from WT orFANCM deficient mutant (Mut) arabidopsis; using anti-FANCM (N) (R3174-1) at RT for 2 h. * indicates a non-specific protein serving as a loading control. |