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Quantity: 100 ul                                                                                          Application: WB

Predicted I Observed M.W.: 88 I 90, 130 kDa                                              Uniprot ID: Q12884

Background:

Seprase (FAP) is a single-pass type II membrane protein belonging to the peptidase S9B family. In association with DPP4, FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. FAP  may have a role in tissue remodeling during development and wound healing, and may contribute to invasiveness in malignant cancers. 

Other Names:

Seprase, 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human FAP. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: