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R0147-1 - FANCI (C1) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 149 kDa Uniprot ID: Q9NVI1 Background: Fanconi anemia, complementation group I (FANCI) is required for maintenance of chromosomal stability. It plays a role in the repair of DNA double-strand breaks by homologous recombination and in the repair of DNA crosslinks. In response to DNA damage it is involved in the S phase and G2 phase checkpoints of the cell cycle. FANCI also promotes FANCD2 ubiquitination and recruitment to DNA repair sites. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage and defective DNA repair. Other Names: FLJ10719, KIAA1794, Protein FACI Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region (distinct from the C-terminal region for R0147-2) of human FANCI. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:5,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
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