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R3500-2 - MYC2 (M) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 68 I 90 kDa Uniprot ID: Q39204 Background: MYC2 is a common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. Together with MYC3 and MYC4, MYC2 controls subsets of JA-dependent responses. MYC2 is also involved in the regulation of ABA-inducible genes under drought stress conditions in cooperation with MYB2. MYC2 can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. MYC2 binds to the MYC recognition site (5'-CACATG-3'), the G-box (5'-CACNTG-3') and Z-box (5'-ATACGTGT-3') of the promoters. MYC2 binds directly to the promoters of the transcription factors PLETHORA1 (PLT1) and PLT2 and represses their expression. MYC2 is a negative regulator of blue light-mediated photomorphogenic growth and blue- and far-red-light regulated gene expression. In contrast, MYC2 is a positive regulator of lateral root formation. MYC2 regulates sesquiterpene biosynthesis. MYC2 is subjected to proteasome-dependent proteolysis. The presence of the destruction element (DE) of MYC2 involved in turnover is required for the proper function of MYC2 to regulate gene transcription. Other Names: Transcription factor MYC2, AtMYC2, Basic helix-loop-helix protein 6, AtbHLH6, bHLH 6, Protein JASMONATE INSENSITIVE 1, R-homologous Arabidopsis protein 1, RAP-1, Transcription factor EN 38, Z-box binding factor 1 protein, bHLH transcription factor bHLH006, rd22BP1, BHLH6, EN38, JAI1, JIN1, RAP1, RD22BP1, ZBF1, At1g32640, F6N18.4 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the middle region of arabidopsis thaliana MYC2 (AT1G32640). Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Arabidopsis thaliana WB: 1:500-1:2,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data:
References cited for this product: 1. Yuan LB, Dai YS, Xie LJ, Yu LJ, Zhou Y, Lai YX, Yang YC, Xu L, Chen QF, and Xiao S. JasmonateRegulatesPlantResponsestoPostsubmergence Reoxygenation through Transcriptional Activation of Antioxidant Synthesis. Plant Physiol. (2017) 173: 1864-1880.
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