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Quantity: 100 ul                                                                                Application: WB

Predicted I Observed M.W.: 238 kDa                                                 Uniprot ID: Q14980

Background:

Nuclear mitotic apparatus protein 1 (NUMA1) is a highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. NUMA1 is required for maintenance and establishment of the mitotic spindle poles, functioning as a tether linking bulk microtubules of the spindle to centrosomes. NUMA1 may also be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.

Other Names:

Nuclear mitotic apparatus protein 1, NuMA protein, SP-H antigen, NUMA

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human NUMA1. Antibodies were purified by affinity purification using immunogen.

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: