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R2906-2 - DSP (C) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 332 kDa Uniprot ID: P15924 Background: Desmoplakin (DSP) belongs to the plakin or cytolinker family. DSP is a major high molecular weight protein of desmosomes. DSP is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Other Names: Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human DSP. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extractsfrom human HeLa, using A) anti-DSP (N) (R2906-1); B) anti-DSP (C) (R2906-2) at RT for 2 h. |