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Quantity: 100 ul                                                                                       Application: WB

Predicted I Observed M.W.: 51 kDa                                                         Uniprot ID: Q99J72

Background:

Apolipoprotein B mRNA-editing complex 3 (APOBEC3) is a DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. APOBEC3 selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. APOBEC3 exhibits antiviral activity against HIV-1, simian immunodeficiency viruses (SIVs), mouse mammary tumor virus (MMTV) and friend murine leukemia virus (FrMLV) and may inhibit the mobility of LTR retrotransposons.

Other Names:

DNA dC->dU-editing enzyme APOBEC-3, Apolipoprotein B mRNA-editing complex 3, Arp3, CEM-15, CEM15

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of mouse APOBEC3. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity: 

Mouse

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: