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Quantity: 100 ul                                                                                 Application: WB

Predicted M.W.: 95 kDa                                                                     Uniprot ID: P01130

Background:

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. LDLR is a single-pass membrane protein, which binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. LDLR can be ubiquitinated by MYLIP leading to its degradation. Mutations in LDLR cause the autosomal dominant disorder, familial hypercholesterolemia.

Other Names:

Low-density lipoprotein receptor, LDL receptor

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human LDLR. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:1,000-1:5,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: