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Quantity: 100 ul                                                                                        Application: WB

Predicted I Observed M.W.: 71 kDa                                                            Uniprot ID: Q84WV6

Background:

MORC1 (Protein MICRORCHIDIA 1) is a mediator of defense signaling triggered by distinct classes of R proteins. MORC1 is required during hypersensitive response (HR) that confers disease resistance to turnip crinkle virus (TCV). MORC1 exhibits ATPase activity. MORC1 is required for pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI), basal resistance, non-host resistance and systemic acquired resistance (SAR). MORC1 binds DNA/RNA in a non-specific manner and exhibits endonuclease activity. MORC1 is probably involved in DNA repair. MORC1 is required for both RPP8- and SSI4-mediated resistance responses, thus being involved in both TIR- and CC-NB-LRR pathways. MORC1 is involved in RNA-directed DNA methylation (RdDM) as a component of the RdDM machinery and required for gene silencing. MORC1 may also be involved in the regulation of chromatin architecture to maintain gene silencing.

Other Names:

Protein MICRORCHIDIA 1, Protein COMPROMISED RECOGNITION OF TCV 1, AtMORC1, CRT1, At4g36290 

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing C-terminal region of arabidopsis thaliana MORC1 (At4g36290). Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Arabidopsis

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications. 

Product Data: