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R3725-2 - GBP1 (C2) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 68 kD Uniprot ID: Q01514
Background: GBP1 (guanylate-binding protein 1) hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. GBP1 exhibits antiviral activity against influenza virus and promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. Other Names: GTP-binding protein 1, Interferon-gamma-inducible protein MAG-1, Interferon-induced guanylate-binding protein 1, GBP-1, mGBP-1, mGBP1, mGBP2b, GBP2b Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of mouse GBP1 protein. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Mouse Tested Applications: WB: 1:500-1:2,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot analysis of equal amounts of protein extractsfrom mouse bone marrow-derived macrophage (BMDM) cellsuntreated (Unt) or treated with IFN-gamma for 20 hr (IFNg) or LPSfor 20 hr as indicated, using anti-GBP1(C2) (R3725-2) at RT for 2 hr.
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