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Quantity: 100 ug                                                                               Application: WB, ELISA

Predicted M.W.: 20 kDa                                                                    Uniprot ID: Q9GZX6

Background:

IL-22 is a member of the IL-10 cytokine superfamily, which are potent mediators of cellular inflammatory responses.  IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens, especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 is rapidly produced by splenic LTi-like cells and can also be produced by Th17 cells. IL-22 plays a role in the coordinated response of both adaptive and innate immune systems. In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the co-expressed cytokine IL-17A.

Other Names:

IL-10-related T-cell-derived-inducible factor, IL-TIF, ZCYTO18, UNQ3099/PRO10096

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human IL-22. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for at least 6 months from date of receipt.

Species Specificity:

Human

Tested Applications:

WB: 1:1,000-1:5,000 (detect recombinant protein)

ELISA:  1:1,000- 1:10,000 (detect native recombinant protein in a direct ELISA assay). 

              Suitable for using as ELISA capture or detection antibodies.

Product Data: