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R0759-1 - SYT5 (N1) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 43 kDa Uniprot ID: O00445
Background: Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. SYT5 regulates the Ca2+-dependent secretion of norepinephrine in PC12 cells. SYT5 is also required for export from the endocytic recycling compartment to the cell surface. Other Names: Synaptotagmin-5, Synaptotagmin V, SytV Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SYT5. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:500-1:1,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
Product Data: Fig 1. Western blot of total cell extracts from human Jurkat, using Ab (R0759-1) at RT for 2 h.
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