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R0829-2 - AXIN2 (C1) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 94 kDa Uniprot ID: Q9Y2T1 Background: Axin-2 (AXIN2) may act as an inhibitor of the Wnt signaling pathway by down-regulating beta-catenin. The deregulation of beta-catenin has been implicated as an important event in the development of a number of malignancies. Defects in AXIN2 are involved in colorectal cancer (CRC) and oligodontia-colorectal cancer syndrome (ODCRCS). Other Names: Axin-2, Axin-like protein, Axil, Axis inhibition protein 2, Conductin Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human AXIN2. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:500-1:1,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
Product Data: Fig 1. Western blot of total cell extracts from human Jurkat, using 2 independent antibodies against two distinct C-terminal regions of human AXIN2 (A: R0829-2; B: R0829-3) at RT for 2 h.
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