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R0901-1 - CASP12 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 39 kDa Uniprot ID: Q6UXS9 Background: Inactive caspase-12 (CASP12) belongs to the peptidase C14A family and has no protease activity. It may reduce cytokine release in response to bacterial lipopolysaccharide during infections. It also reduces activation of NF-kappa-B in response to TNF. The variant Arg-125 (Csp12-L) of CASP12 may increase the susceptibility to sever sepsis, and may also increase the mortality rate in sepsis patients. Other Names: Inactive caspase-12, CASP-12 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human CASP12. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human Tested Applications: WB: 1:500-1:1,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
Product Data: Fig 1. Western blot of total cell extracts from human HeLa, using Ab (R0901-1) at RT for 2 h.
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