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Quantity: 100 ul                                                                                 Application: WB

Predicted M.W.: 120 kDa                                                                  Uniprot ID: Q9H3R0

Background:

Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that belongs to the JHDM3 histone demethylase family. It specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. KDM4C demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, but not mono- and dimethylated residues.

Other Names:

Lysine-specific demethylase 4C, Gene amplified in squamous cell carcinoma 1 protein, GASC-1 protein, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, GASC1, JHDM3C, JMJD2C, KIAA0780

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human KDM4C. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human

Tested Applications: 

WB: 1:500-1:1,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: