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R1080-1 - ZBTB5 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted | Observed MW: 74 | 80 kDa Uniprot ID: Q15916 Background: Zinc finger and BTB domain-containing protein 5 (ZBTB5) is a Krüppel like zinc finger transcription repressor containing a POZ domain. ZBTB5 is expressed in retinoblastoma and muscle cancer tissues. ZBTB5 is a potent transcription repressor of cell cycle arrest gene p21 and a potential proto-oncogene stimulating cell proliferation. ZBTB5 may regulate transcriptional repression through chromatin remodeling and histone deacetylation (Koh D. et al., 2009, JBC 284:19856). Other Names: Zinc finger and BTB domain-containing protein 5 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human ZBTB5. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:500-1:2,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: from mouse brain, using Ab (R1080-1) at RT for 2 h. |