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R1463-1 - SIX3 (C1) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted | Observed MW: 35 kDa Uniprot ID: O95343 Background: Homeobox protein SIX homeobox 3 (SIX3) belongs to the SIX/Sine oculis homeobox family. SIX3 is crucial in embryonic development by providing necessary instructions for the formation of the forebrain and eye development. SIX3 is a transcription factor that binds to DNA, and it regulates the activities of other protein factors, such as WNT1 and PAX6. Defects in SIX3 are the cause of holoprosencephaly type 2 (HPE2). Other Names: Homeobox protein SIX3, Sine oculis homeobox homolog 3 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human SIX3. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:500-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: (A) human HeLa, (B) human Jurkat, (C) mouse thymus, using Ab (R1463-1) at RT for 2 h. |