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R0034-1 - SUV39H2 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted M.W.: 47 kDa Uniprot ID: Q9H5I1
Background: SUV39H2 is a histone methyltransferase that specifically trimethylates ‘Lys-9’ of histone H3. It achieves this by using monomethylated ‘Lys-9’ as a substrate. H3 ‘Lys-9’ trimethylation is a specific tag for epigenetic transcriptional repression. SUV39H2 primarily functions in heterochromatin regions where it plays a pivotal role in the establishment of constitutive heterochromatin at pericentric and telomere regions. Other Names: RP11-2K17.2, FLJ23414, KMT1B Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SUV39H2. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 40% Glycerol, 100 ug/mg BSA, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:5,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot of total cell extracts from human 293T,using Ab (R0034-1) at RT for 2 h. |