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Quantity: 100 ul                                                                                          Application: WB

Predicted | Observed MW: 84 I 75 kDa                                                       Uniprot ID: P35711

Background:

Transcription factor SOX5 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX5 may act as a transcriptional regulator after forming a protein complex with other proteins. SOX5 binds specifically to the DNA sequence 5'-AACAAT-3', and activates transcription of COL2A1 and AGC1 in vitro. SOX5 may also play a role in chondrogenesis. Several isoforms of SOX5 have been identified.

Other Names:

Transcription factor SOX-5, SRY (sex determining region Y)-box 5, L-SOX5

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human SOX5. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:500-1:2,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: