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R0586-1 - PD-L1 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted | Observed MW: 33 | 33, 50-60 kDa Uniprot ID: Q9EP73
Background: Programmed cell death 1 ligand 1 (CD274) is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily and the BTN/MOG family. CD274 is involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. CD274’s interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. Other Names: Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1, CD274, Cd274 Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of mouse PD-L1. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: Fig 1. Western blot analysis of equal amounts of protein extracts from mouse bone marrow-derived macrophages, untreated (Unt) or treated with Interferon-gamma (IFNg ,10 ng/ml) or LPS (20 ng/ml) for 20 hrs, using anti-PD-L1(N) (R0586-1) at RT for 2 h.
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