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Uniprot ID: Q99592                                                                                     Application: WB

Predicted | Observed MW: 58 kDa                                                             

Quantity:        50 ul ZNF238 (N2) (R0702-2) Rabbit Polyclonal Antibody &

                      50 ul ZNF238 (C) (R0702-3) Rabbit Polyclonal Antibody

Product Introduction:

vPair^TM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPair^TM antibodies in the same assay can validate signal specificity since vPair^TM antibodies recognize two independent epitopes of the same protein. Different sets of vPair^TM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.

Background:

Zinc finger protein 238 (ZNF238) is a transcriptional repressor that plays a role in various developmental processes such as myogenesis and brain development. ZNF238 plays a key role in myogenesis by directly repressing the expression of ID2 and ID3, 2 inhibitors of skeletal myogenesis. ZNF238 is also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes. ZN237 may also play a role in the organization of chromosomes in the nucleus.

Other Names:

Zinc finger protein 238, 58 kDa repressor protein, Transcriptional repressor RP58, Translin-associated zinc finger protein 1, TAZ-1, Zinc finger and BTB domain-containing protein 18, Zinc finger protein C2H2-171, RP58, TAZ1, ZBTB18

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal [ZNF238 (N2) (R0702-2)] or the C-terminal [ZNF238 (C) (R0702-3)] region of human ZNF238. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: