Abiocode Logo

Quantity: 100 ul                                                                                       Application: WB

Predicted | Observed MW: 53 | 60 kDa                                                    Uniprot ID: Q8WTR8

Background:

Netrin-5 (NTN5) is a member of the Netrin family, which are secreted proteins involved in axon guidance. Structurally, netrin resembles laminin. NTN5 contains 3 laminin EGF-like domains and 1 NTR domain. Netrins are chemotropic; a growing axon will either move towards or away from a higher concentration of netrin. Though the detailed mechanism of axon guidance is not fully understood, it is known that netrin attraction is mediated through UNC-40/DCC cell surface receptors and repulsion is mediated through UNC-5 receptors. Netrins also act as growth factors to promote cell growth. Mice deficient in netrin fail to form the hippocampal comissure or the corpus callosum.

Other Names:

Netrin-5, Netrin-1-like protein, Netrin 5

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human NTN5. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: