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Uniprot ID: P25118 (R1682-3) and P19438 (R1682-5)                               Application: WB

Predicted I Observed M.W.: 50 I 58 kDa                                                    

Quantity:        50 ul TNFRSF1A (N1) (R1682-3) Rabbit Polyclonal Antibody &

                         50 ul TNFRSF1A (N3) (R1682-5) Rabbit Polyclonal Antibody

Product Introduction:

vPair^TM antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Abiocode to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody-based assays. The use of a pair of fully characterized vPair^TM antibodies in the same assay can validate signal specificity since vPair^TM antibodies recognize two independent epitopes of the same protein. Different sets of vPair^TM antibodies are developed at Abiocode to work with specific applications, including antibody arrays, Western blot, IP-Western, ChIP, IHC, and FACS.

Background:

TNFRSF1A is the receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha.  TNFRSF1A is activated by the adapter molecule FADD recruiting caspase-8.  Defects in TNFRSF1A are the cause of familial Hibernian fever, also known as tumor necrosis factor receptor-associated periodic syndrome.

Other Names:

TNFAR, TNFR1

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing 2 distinct N-terminal regions of human or mouse TNFRSF1A. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt. 

Species Specificity:

Human, Mouse

Tested Applications: 

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modification

Product Data: