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Quantity: 100 ul                                                                     Application: WB

Predicted I Observed M.W.: 26 I 30 kDa                           Uniprot ID: Q99801

Background:

NKX3.1 is a transcription factor, which binds preferentially the consensus sequence 5’-TAAGT[AG]-3’ and can behave as a transcriptional repressor.  NK3.1 plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate.  NKX3.1 acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Other Names:

NKX3-1, NKX3A

Source and Purity:

Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of mouse NKX3.1. Antibodies were purified by affinity purification using immunogen. 

Storage Buffer and Condition:

Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN₃. Store at -20 °C. Stable for 6 months from date of receipt.

Species Specificity:

Human, Mouse

Tested Applications:

WB: 1:1,000-1:3,000 (detect endogenous protein*)

*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Product Data: