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R1482-1 - CSNK1E (C1) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB Predicted I Observed M.W.: 47 I 42 kDa Uniprot ID: P49674 Background: CSNK1E has been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CSNK1E also phosphorylates a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm. Inhibits cytokine-induced granuloytic differentiation. Other Names: Casein kinase I isoform epsilon, CKIE, CKIepsilon, HCKIE Source and Purity: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human CSNK1E. Antibodies were purified by affinity purification using immunogen. Storage Buffer and Condition: Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt. Species Specificity: Human, Mouse Tested Applications: WB: 1:1,000-1:3,000 (detect endogenous protein*) *: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Product Data: (A, D) mouse brain, (B) mouse thymus, (C, E) human HeLa; using 2 independent Abs against 2 distinct C-terminal regions of human CSNK1E at RT for 2 h.
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