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R1425-1 - MAP2K3 (N) Antibody, Rabbit Polyclonal
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Quantity: 100 ul Application: WB
Predicted I Observed M.W.: 39 I 42 kDa Uniprot ID: P46734
Background:
MAP2K3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. MAP2K3 is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. MAP2K3 phosphorylates and thus activates MAPK14/p38-MAPK. MAP2K3 can be activated by insulin, and is necessary for the expression of glucose transporter. Abundant expression of MAP2K3 is seen in the skeletal muscles.
Other Names:
Dual specificity mitogen-activated protein kinase kinase 3, MAPK/ERK kinase 3, Stress-activated protein kinase kinase 2, MEK3, MKK3, PRKMK3, SKK2
Source and Purity:
Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the N-terminal region of human MAP2K3. Antibodies were purified by affinity purification using immunogen.
Storage Buffer and Condition:
Supplied in 1 x PBS (pH 7.4), 100 ug/ml BSA, 40% Glycerol, 0.01% NaN3. Store at -20 °C. Stable for 6 months from date of receipt.
Species Specificity:
Human, Mouse Tested Applications:
WB: 1:1,000-1:3,000 (detect endogenous protein*)
*: The apparent protein size on WB may be different from the calculated M.W. due to modifications.
Product Data: Fig 1. Western blot of total cell extracts from (A) human HeLa, (B) human Jurkat, (C) mouse thymus; using anti-MAP2K3 (N) (R1425-1) at RT for 2 h.
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